Strontium Supports Human Sperm Capacitation but Not Follicular Fluid-Induced Acrosome Reaction1

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P-56: Effect of Cissampelos Capensis Rhizome Extract on Human Sperm Capacitation and Acrosome Reaction

s:2086:"Background: Cissampelos capensis, is commonly known by the Afrikaans name "dawidjies" and is the most important and best known medicinal plant of the family Menispermaceae used by the Khoisan and other rural people in the western regions of South Africa. Among numerous other ailments, it is taken to treat male fertility problems. The aim of this study was to investigate the effects of C...

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Src activation triggers capacitation and acrosome reaction but not motility in human spermatozoa.

BACKGROUND Protein tyrosine phosphorylation is one of the main processes associated with sperm activation. Although this process and its targets have been well characterized, only few tyrosine kinases have been identified so far and their roles in spermatozoa are still largely unknown. In this study, we report the presence and localization of Src kinase in ejaculated human spermatozoa and inves...

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Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction

Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur during capacitation. In this article, we have reviewed the data from our and other laboratories, a...

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Protein kinases in mammalian sperm capacitation and the acrosome reaction.

Binding to the zona pellucida of an egg stimulates the spermatozoon to undergo the acrosome reaction, a process that enables it to penetrate the egg. Before this binding, the spermatozoon undergoes a series of biochemical transformations in the female reproductive tract, collectively called capacitation. Only capacitated spermatozoa can bind to the zona pellucida and undergo the acrosome reacti...

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Effect of Cissampelos capensis rhizome extract on human sperm capacitation and acrosome reaction

Introduction Cissampelos capensis, is commonly known by the Afrikaans name ‟dawidjies” or ‟dawidjieswortel”. C. capensis is the most important and best known medicinal plant of the family Menispermaceae used by the Khoisan and other rural people in the western regions of South Africa. Among numerous other ailments, it is traditionally taken to treat male fertility problems. Yet, no studies have...

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ژورنال

عنوان ژورنال: Biology of Reproduction

سال: 1999

ISSN: 0006-3363,1529-7268

DOI: 10.1095/biolreprod61.3.673